Home Network Structure Members Area Sitemap Contact Us Help  












Newsletter
 
Public databases with primary data are ...
  useful
  a lot of work
  too much work
  not reliable due to lack of validation
Integrated Functional Genomics in Mutant Mouse Models as Tools to Investigate the Complexity of Human Immunological Disease (MUGEN)
Immunological diseases encompass a wide variety of disorders, affecting a steadily increasing proportion of people living in modern societies. Immunological diseases include multiple sclerosis, systemic lupus, rheumatoid arthritis and cancer.During the past decade, dramatic advances have been made in understanding mechanisms regulating the immune system, its pathological processes, and processes of immune deviation. As such, it was recognized that systemic or organ-specific inflammatory, infectious and autoimmune conditions share basic mechanisms of initiation and progression. Further elucidation of these mechanisms promises to be of very high value for diagnosis and treatment of these disorders.
MUGEN Network News
Novel more efficient therapeutic approaches against Crohn's disease
  Using a unique murine model for human Crohn's disease, MUGEN's NoE participants [G. Kollias, D. Kontoyiannis (Fleming), W. Mόller (HZI), B. Malissen (CNRS]) identified key molecules that control T lymphocyte migration to the small intestine. Their discovery brings into focus the use of novel, more efficient therapeutic approaches against Crohn's disease.
more info
 
2nd MUGEN Phenotyping Technological Workshop
  The MUGEN management office would like to announce the first call for the 2nd MUGEN Phenotyping Technological Workshop. The workshop will take place at Manchester University on the 16th and 17th of June 2008 at the University of Manchester.
more info
 
The future of gene therapy compromised?
  Lausanne, 12 March 2008. MUGEN participant Professor Jurg Tschopp and his colleagues have reported that activation of the inflammasome, a multi-protein complex involved in the innate immune response against many pathogens, is also important for the generation of an effective inflammatory response to adenoviruses and other DNA viruses.
more info
MUGEN's Technology Cores
Copyright 2008 © Biomedical Sciences Research Centre "Al. Fleming" | Disclaimer | Privacy Policy