Evidence for distinct forms of compulsivity in the SAPAP3 mutant-mouse model for obsessive-compulsive disorder.

Specific mechanisms underlying the compulsive behaviors of obsessive-compulsive disorder (OCD) is unknown. It has been suggested that these compulsivity may have its origin in cognitive dysfunction such as impaired information processing feedback – received after completion of goal-directed action. Signal attenuation (SA) models such task processing deficits in animals by weakening the strength of the relationship between food and the gift audiovisual feedback (signal) served after the performance operant response. The compulsive as resulting from the SA respond well characterized in mice, but so far not established in rats, a species strong genetic OCD existing models.

Thus, first, we show that the task of SA can be implemented in mice and showed that the damping feedback related reward responses produce similar behavior in C57BL6 mice as reported previously in mice. Secondly, we tested the hypothesis that SAPAP3 KO mice (SAPAP3 – / -), prone to show some OCD-like disorders including excessive treatment, showed an increase in compulsive-like behaviors in their task of SA compared with wild-type littermates (WT). However, measures compulsivity-related tasks in SAPAP3 – / – and WT did not produce a significant difference, following either SA or for the extinction of “ordinary” of instrumental behavior.

Thus, compulsive-like behaviors instrumental follows distortion feedback is not potential in compulsive care mice, involving in particular that a) deficits common in the processing of feedback is not related to the treatment of excessive SAPAP3 – / -, and b) a different manifestation of compulsivity may be driven by independent mechanisms.Significance Statement signal attenuation (SA) duty is established for a rat behavioral paradigm that promotes compulsivity.

First, we show that SA tasks can also be applied to the processing of feedback tests on mice. Second, we investigate if SAPAP3 mutant mice, a model of animal genetic highly validated for obsessive-compulsive disorder (OCD), exhibit compulsive respond to the task exacerbated SA. However, we did not find an increased compulsivity feedback-induced mutant SAPAP3. Thus, our results indicate the presence of various types of compulsivity (ie, genetically induced behavior compared compulsivity) possibly boosted by an independent mechanism.

The effect of reduced connexin43 function in the development of the skull in Cx43I130T / + mouse mutant models oculodentodigital dysplasia.

Oculodentodigital dysplasia (ODDD) is a disease caused by mutations in the gene that encodes GJA1 gap-junctional protein connexin43 (Cx43). ODDD affects multiple organs, but the typical craniofacial anomalies. However, details about the time the phenotypic presentation of this disorder and their correspondence with potential cellular changes is not complete.

Here, we do the first assessment of the development of the craniofacial phenotype ODDD in Cx43I130T / + mouse model and showed that the phenotypic features commonly found in commonly found in patients with these disorders arise in mice between E17.5 and birth and becoming deeper with age. Using mice heterozygous for the mutation I130T of Gja1 we provide a detailed analysis of the craniofacial phenotype in this ODDD models using shape analysis based on micro-CT images.

Optimax First Strand cDNA Synthesis Kit
K4201100	Biochain	100 rnx	EUR 419

First-Strand cDNA Synthesis SuperMix for PCR
abx098018-50rxns20ulSystems	Abbexa	50 rxns × 20 ul Systems	EUR 578
Shipped within 5-10 working days.

First-Strand cDNA Synthesis SuperMix (cDNA up to 12 kb)
20-abx09801620ulSystems	Abbexa	EUR 620.00 EUR 523.00	100 rxns × 20 ul Systems 50 rxns × 20 ul Systems
Shipped within 5-10 working days.

First-Strand cDNA Synthesis SuperMix (cDNA up to 15 kb)
20-abx09802120ulSystems	Abbexa	EUR 871.00 EUR 662.00	100 rxns × 20 ul Systems 50 rxns × 20 ul Systems
Shipped within 5-10 working days.

igScript First Strand cDNA Synthesis Kit - 25 Reactions
4312	Intact Genomics	1/EA	EUR 149

igScript First Strand cDNA Synthesis Kit - 100 Reactions
4314	Intact Genomics	1/EA	EUR 378

Accuris qMAX First Strand cDNA Synthesis Flex Kit
PR2110-200	BenchMark	1 PC	EUR 337.75
To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Accuris qMAX First Strand cDNA Synthesis Flex Kit
PR2110-50	BenchMark	1 PC	EUR 132.79
To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Accuris qMAX First Strand cDNA Synthesis Flex Kit
PR2110-S	BenchMark	1 PC	EUR 72.98
To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

All-in-One First-Strand cDNA Synthesis SuperMix for PCR
abx098023-50rxns20ulSystems	Abbexa	50 rxns × 20 ul Systems	EUR 732
Shipped within 5-10 working days.

cDNA from Human Tumor Tissue: Kidney
C1235142	Biochain	40 reactions	EUR 540
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from hypertension: Kidney
C1236142Hd-2	Biochain	40 reactions	EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Lupus: Kidney
C1236142Lup	Biochain	40 reactions	EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

HiFiScript 1st Strand cDNA Synthesis Kit
W2569-10	101Bio	NULL	EUR 0

HiFiScript 1st Strand cDNA Synthesis Kit
W2569-100	101Bio	NULL	EUR 0

HiFiScript 1st Strand cDNA Synthesis Kit
W2569-30	101Bio	NULL	EUR 0

cDNA from Human Diabetic Tissue: Kidney
C1236142Dia	Biochain	40 reactions	EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Matching Pair - cDNA from Human Primary Tumor and Normal Tissue: Kidney
C8235142-PP	Biochain	10 reactions x2	EUR 499
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Liver Cirrhosis: Kidney
C1236142Lcs	Biochain	40 reactions	EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Second Strand cDNA Synthesis Kit-dNTP based
G475	ABM	25 x 50 ul reactions	EUR 389

HiScript II 1st Strand cDNA Synthesis Kit
R211-01	Vazyme	50 rxn (20 μl/rxn)	EUR 184

HiScript II 1st Strand cDNA Synthesis Kit
R211-02	Vazyme	100 rxn (20 μl/rxn)	EUR 251

Human Kidney Tumor lysate
HTL-1324	Alpha Diagnostics	1 mg	EUR 773

Matching Pair - cDNA from Human Primary and Matched Metastatic Tumor Tissue: Kidney
C8235142-PM	Biochain	10 reactions x2	EUR 984
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Kidney
C1234142	Biochain	40 reactions	EUR 376
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Human Tumor Tissue: Breast cDNA
HT05-090	Alpha Diagnostics	10 rxn	EUR 415

Second-Strand cDNA Synthesis Kit-dNTP/dUTP based
G476	ABM	25 x 50 ul reactions	EUR 478

cDNA from Mouse Normal Tissue: Kidney
C1334142	Biochain	40 reactions	EUR 376
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Rat Normal Tissue: Kidney
C1434142	Biochain	40 reactions	EUR 376
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Dog Normal Tissue: Kidney
C1734142	Biochain	40 reactions	EUR 376
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

miRNA 1st Strand cDNA Synthesis Kit (by stem-loop)
MR101-01	Vazyme	50 rxn (20 μl/rxn)	EUR 198

miRNA 1st Strand cDNA Synthesis Kit (by stem-loop)
MR101-02	Vazyme	100 rxn (20 μl/rxn)	EUR 285

HiScript III 1st Strand cDNA Synthesis Kit (+gDNA wiper)
R312-01	Vazyme	50 rxn (20 μl/rxn)	EUR 239

HiScript III 1st Strand cDNA Synthesis Kit (+gDNA wiper)
R312-02	Vazyme	100 rxn (20 μl/rxn)	EUR 310

cDNA from Human Tumor Tissue: Adrenal
C1235004-10	Biochain	10 reactions	EUR 282
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Tumor Tissue: Bladder
C1235010-10	Biochain	10 reactions	EUR 282
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Tumor Tissue: Bone
C1235023-10	Biochain	10 reactions	EUR 282
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Tumor Tissue: Brain
C1235035-10	Biochain	10 reactions	EUR 282
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Tumor Tissue: Breast
C1235086	Biochain	40 reactions	EUR 540
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Tumor Tissue: Colon
C1235090	Biochain	40 reactions	EUR 540
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Tumor Tissue: Liver
C1235149	Biochain	40 reactions	EUR 540
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Tumor Tissue: Lung
C1235152	Biochain	40 reactions	EUR 540
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Tumor Tissue: Lymphoma
C1235161-10	Biochain	10 reactions	EUR 282
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Tumor Tissue: Mesenchymoma
C1235164-10	Biochain	10 reactions	EUR 282
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Tumor Tissue: Nose
C1235178-10	Biochain	10 reactions	EUR 282
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Tumor Tissue: Ovary
C1235183-10	Biochain	10 reactions	EUR 494
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Tumor Tissue: Pancreas
C1235188-10	Biochain	10 reactions	EUR 282
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Tumor Tissue: Parathyroid
C1235189-10	Biochain	10 reactions	EUR 494
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Tumor Tissue: Prostate
C1235201-10	Biochain	10 reactions	EUR 282
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Tumor Tissue: Rectum
C1235206-10	Biochain	10 reactions	EUR 282
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Tumor Tissue: Skin
C1235218-10	Biochain	10 reactions	EUR 282
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Tumor Tissue: Melanoma
C1235218A-10	Biochain	10 reactions	EUR 282
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Tumor Tissue: Stomach
C1235248	Biochain	40 reactions	EUR 540
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Tumor Tissue: Uterus
C1235274	Biochain	40 reactions	EUR 540
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Monkey (Rhesus) Normal Tissue: Kidney
C1534142	Biochain	40 reactions	EUR 376
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Monkey (Cynomolgus) Normal Tissue: Kidney
C1534142-Cy	Biochain	40 reactions	EUR 376
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Paraffin Tissue Section - Human Kidney Tumor: Wilms' Tumor
T2235142-7	Biochain	5 slides	EUR 257
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Human Cancer PrimaCell9: Kidney Tumor Cells
2-96032	CHI Scientific	1 Kit	Ask for price

Frozen Tissue Section - Human Tumor: Kidney
T1235142	Biochain	5 slides	EUR 338
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Paraffin Tissue Section - Human Kidney Tumor
T2235142	Biochain	5 slides	EUR 257
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

cDNA from Human Tumor Tissue: Skeletal Muscle
C1235171-10	Biochain	10 reactions	EUR 282
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Tumor Cell Line: A431
C1255801	Biochain	40 reactions	EUR 376
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Tumor Cell Line: Hela
C1255811	Biochain	40 reactions	EUR 376
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Tumor Cell Line: Jurkat
C1255815	Biochain	40 reactions	EUR 376
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Tumor Cell Line: Raji
C1255840	Biochain	40 reactions	EUR 376
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Human Kidney Slide (Tumor) (5 slides/pk)
HTS-10402	Alpha Diagnostics	1 pk	EUR 286

Membrane Protein from Human Tumor Tissue: Kidney
P3235142	Biochain	0.1 mg	EUR 408
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Total Protein from Human Tumor Tissue: Kidney
P1235142	Biochain	1 mg	EUR 320
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Total RNA from Human Tumor Tissue: Kidney
R1235142-50	Biochain	50 ug	EUR 351
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Tumor Tissue: Lymphoma, Hodgkin's Disease
C1235161A-10	Biochain	10 reactions	EUR 282
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Tumor Cell Line: K 562
C1255820	Biochain	40 reactions	EUR 376
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Tumor Cell Line: MCF 7
C1255830	Biochain	40 reactions	EUR 376
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Human Cancer PrimaCell9: Kidney Tumor Cells Growth Medium
9-46032	CHI Scientific	5 x 100 ml	Ask for price

cDNA from Human Tumor Tissue: Lymphoma, Non-Hodgkin's Disease
C1235161B-10	Biochain	10 reactions	EUR 282
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Genomic DNA from Human Tumor Tissue: Kidney Tumor, from a single donor
D1235142	Biochain	50 ug	EUR 446
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Human Cancer Tissue Preparation Buffer 9: Kidney Tumor Cells
9-80032	CHI Scientific	1 x 100 ml	Ask for price

Paraffin Tissue Section - Human Kidney Tumor: Clear cell carcinoma
T2235142-2	Biochain	5 slides	EUR 257
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Paraffin Tissue Section - Human Kidney Tumor: Renal Cell Carcinoma
T2235142-5	Biochain	5 slides	EUR 257
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Paraffin Tissue Section - Human Kidney Tumor: Papillary Renal Cell Carcinoma
T2235142-4	Biochain	5 slides	EUR 257
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Matching Pair - Total Protein from Human Primary Tumor and Metastatic Tumor Tissue (PM): Kidney
P8235142-PM	Biochain	0.2 mg x2	EUR 1228
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Kidney Tumor Tissue Array - 12 cases of kidney cancer paired with adjacent normal tissues
Z7020053	Biochain	5 slides	EUR 938
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Matching Pair - cDNA from Human Primary Tumor and Normal Tissue: Breast
C8235086-PP	Biochain	10 reactions x2	EUR 499
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Matching Pair - cDNA from Human Primary Tumor and Normal Tissue: Colon
C8235090-PP	Biochain	10 reactions x2	EUR 499
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Matching Pair - cDNA from Human Primary Tumor and Normal Tissue: Liver
C8235149-PP	Biochain	10 reactions x2	EUR 499
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Matching Pair - cDNA from Human Primary Tumor and Normal Tissue: Lung
C8235152-PP	Biochain	10 reactions x2	EUR 499
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Matching Pair - cDNA from Human Primary Tumor and Normal Tissue: Rectum
C8235206-PP	Biochain	10 reactions x2	EUR 499
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Matching Pair - cDNA from Human Primary Tumor and Normal Tissue: Stomach
C8235248-PP	Biochain	10 reactions x2	EUR 499
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Human Kidney PrimaCell2: Normal Kidney Epithelial Cells
2-96075	CHI Scientific	1 Kit	Ask for price

Matching Pair - DNA from Human Primary and Metastatic Tumor Tissue: Kidney
D8235142-PM-10	Biochain	2x10 ug	EUR 610
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Matching Pair - DNA from Human Primary Tumor and Normal Tissue: Kidney
D8235142-PP-10	Biochain	2x10 ug	EUR 387
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Human eNOS cDNA probe
eNOS51-D-2	Alpha Diagnostics	2 ug	EUR 445

Matching Pair - cDNA from Human Primary and Matched Metastatic Tumor Tissue: Breast
C8235086-PM	Biochain	10 reactions x2	EUR 984
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Matching Pair - cDNA from Human Primary and Matched Metastatic Tumor Tissue: Colon
C8235090-PM	Biochain	10 reactions x2	EUR 984
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Matching Pair - cDNA from Human Primary and Matched Metastatic Tumor Tissue: Liver
C8235149-PM	Biochain	10 reactions x2	EUR 984
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Matching Pair - cDNA from Human Primary and Matched Metastatic Tumor Tissue: Lung
C8235152-PM	Biochain	10 reactions x2	EUR 984
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Matching Pair - cDNA from Human Primary and Matched Metastatic Tumor Tissue: Rectum
C8235206-PM	Biochain	10 reactions x2	EUR 984
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Matching Pair - cDNA from Human Primary and Matched Metastatic Tumor Tissue: Stomach
C8235248-PM	Biochain	10 reactions x2	EUR 984
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Kidney Tumor Tissue Array - 48 cases of uninvolved and cancerous tissues of the kidney in duplicates
Z7020055	Biochain	5 slides	EUR 1381
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Out At First Protein Homolog (OAF) Antibody
abx027798-400ul	Abbexa	400 ul	EUR 523
Shipped within 5-10 working days.

Out At First Protein Homolog (OAF) Antibody
abx027798-80l	Abbexa	80 µl	EUR 286
Shipped within 5-10 working days.

Out At First Protein Homolog (OAF) Antibody
abx146027-100ug	Abbexa	100 ug	EUR 391
Shipped within 5-10 working days.

Matching Pair - Total RNA from Human Primary and Metastatic Tumor Tissue: Kidney
R8235142-PM-10	Biochain	2x10 ug	EUR 650
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Matching Pair - Total RNA from Human Primary Tumor and Normal Tissue: Kidney
R8235142-PP-10	Biochain	2x10 ug	EUR 439
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Matching Pair - Frozen Tissue Section - Human Primary Tumor and Normal (PP): Kidney
T6235142-PP	Biochain	5 slides x2	EUR 599
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Matching Pair - Paraffin Tissue Section - Human Primary Tumor and Normal (PP): Kidney
T8235142-PP	Biochain	5 slides x2	EUR 403
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Human Kidney PrimaCell2: Normal Kidney Epithelial Cells Growth Medium
9-46075	CHI Scientific	5 x 100 ml	Ask for price

Human Kidney Tissue Lysate
30R-AK003	Fitzgerald	150 ug	EUR 219
Description: Fresh tissue lysate isolated from human kidney

cDNA Synthesis SuperMix
20-abx09801420ulSystems	Abbexa	EUR 565.00 EUR 481.00	100 rxns × 20 ul Systems 50 rxns × 20 ul Systems
Shipped within 5-10 working days.

Evo? cDNA Kit
M1164-100	Biovision		EUR 294

Evo? cDNA Kit
M1164-25	Biovision		EUR 234

Novo? cDNA Kit
M1165-100	Biovision		EUR 354

Novo? cDNA Kit
M1165-25	Biovision		EUR 267

Evo? cDNA Supermix
M1168-100	Biovision		EUR 381

Evo? cDNA Supermix
M1168-25	Biovision		EUR 267

Novo? cDNA Supermix
M1169-100	Biovision		EUR 441

Novo? cDNA Supermix
M1169-25	Biovision		EUR 289

Human Adult cDNA Tissue: Lung
HA-152	Alpha Diagnostics	10 rxn	EUR 415

Human Adult cDNA Tissue: Skin
HA-218	Alpha Diagnostics	10 rxn	EUR 415

Human Adult cDNA Tissue: Testis
HA-260	Alpha Diagnostics	10 rxn	EUR 415

Mouse Kidney PrimaCell2: Normal Kidney Epithelial Cells
2-82057	CHI Scientific	1 Kit	Ask for price

Rat Kidney PrimaCell2: Normal Kidney Epithelial Cells
2-82556	CHI Scientific	1 Kit	Ask for price

Matching Pair - Total Protein from Human Primary Tumor and Normal Tissue (PP): Kidney
P8235142-PP	Biochain	0.2 mg x2	EUR 639
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Matching Pair - Frozen Tissue Section - Human Primary and Matched Metastatic Tumor (PM): Kidney
T6235142-PM	Biochain	5 slides x2	EUR 743
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Matching Pair - Paraffin Tissue Section - Human Primary and Matched Metastatic Tumor (PM): Kidney
T8235142-PM	Biochain	5 slides x2	EUR 639
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Human OAF (Out at first protein homolog) ELISA Kit (CUSTOM)
ELI-38218h	Lifescience Market	96 Tests	EUR 824

Human Kidney Tissue Preparation Buffer 2: Normal Kidney Epithelial Cells
9-80075	CHI Scientific	1 x 100 ml	Ask for price

Males-Absent On The First Protein (MOF) Antibody
abx235266-100ug	Abbexa	100 ug	EUR 481
Shipped within 5-12 working days.

cDNA from Plant Normal Tissue: cDNA from Plant: Arabidopsis
C1634310	Biochain	40 reactions	EUR 621
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Plant Normal Tissue: cDNA from Plant: Corn
C1634330	Biochain	40 reactions	EUR 621
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Plant Normal Tissue: cDNA from Plant: Orange
C1634340	Biochain	40 reactions	EUR 621
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Plant Normal Tissue: cDNA from Plant: Potato
C1634350	Biochain	40 reactions	EUR 621
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Plant Normal Tissue: cDNA from Plant: Rice
C1634360	Biochain	40 reactions	EUR 621
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Plant Normal Tissue: cDNA from Plant: Wheat
C1634390	Biochain	40 reactions	EUR 621
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Autobioluminescent Human Kidney Cells (HEK293)
ASE-5902	Applied StemCell	1 ml	EUR 1670
Description: 6 month

Human Cancer PrimaCell9: Kidney Tumor Cells Growth Supplements with Serum (for 500 ml medium)
9-47032	CHI Scientific	1 Set	Ask for price

Multiple Tumor Tissue Array - Ovary, Bladder, Breast, Kidney, Uterus, and Lung tumors, plus 12 tumor/normal pairs
T8235714d-2	Biochain	2 slides	EUR 307
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Multiple Tumor Tissue Array - Ovary, Bladder, Breast, Kidney, Uterus, and Lung tumors, plus 12 tumor/normal pairs
T8235714d-5	Biochain	5 slides	EUR 579
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Multiple Tumor Tissue Array - Kidney, Colon, Esophagus, Liver, Rectum and Stomach tumors, plus 12 tumor/normal pairs
T8235715d-2	Biochain	2 slides	EUR 307
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Multiple Tumor Tissue Array - Kidney, Colon, Esophagus, Liver, Rectum and Stomach tumors, plus 12 tumor/normal pairs
T8235715d-5	Biochain	5 slides	EUR 579
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Multiple Tumor Tissue Array - Bladder, Colon, Kidney, Lung, Stomach, and Uterus tumors, plus 12 tumor/normal pairs
T8235716d-5	Biochain	5 slides	EUR 579
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Kidney Cancer Exosome
P141-KN	101Bio	NULL	EUR 0

Multiple Tumor Tissue Array - Bladder, Colon, Kidney, Lung, Stomach, and Uterus tumors
T8235716d-2	Biochain	2 slides	EUR 307
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

cDNA from Plant Normal Tissue: cDNA from Plant: Soy bean
C1634370	Biochain	40 reactions	EUR 621
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Diabetic Tissue: Brain
C1236035Dia	Biochain	40 reactions	EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Diabetic Tissue: Colon
C1236090Dia	Biochain	40 reactions	EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Diabetic Tissue: Esophagus
C1236106Dia	Biochain	40 reactions	EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Diabetic Tissue: Heart
C1236122Dia	Biochain	40 reactions	EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Diabetic Tissue: Liver
C1236149Dia	Biochain	40 reactions	EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Diabetic Tissue: Lung
C1236152Dia	Biochain	40 reactions	EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Diabetic Tissue: Pancreas
C1236188Dia	Biochain	40 reactions	EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Diabetic Tissue: Skin
C1236218Dia	Biochain	40 reactions	EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Diabetic Tissue: Spleen
C1236246Dia	Biochain	40 reactions	EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Diabetic Tissue: Stomach
C1236248Dia	Biochain	40 reactions	EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA Probe Diluent Solution
AR0063	BosterBio	5mL	EUR 106

cDNA from Arteriosclerosis: Aorta
C1236012Hd-4	Biochain	40 reactions	EUR 811
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from hypertension: Artery
C1236013Hd-2	Biochain	40 reactions	EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Arteriosclerosis: Artery
C1236013Hd-4	Biochain	40 reactions	EUR 811
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from hypertension: Vein
C1236020Hd-2	Biochain	40 reactions	EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Lupus: Colon
C1236090Lup	Biochain	40 reactions	EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from hypertension: Heart
C1236122Hd-2	Biochain	40 reactions	EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Lupus: Heart
C1236122Lup	Biochain	40 reactions	EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

The results showed that in addition to differences in facial bone morphology no significant differences in the basic shape of the skull. mutant mice display delayed ossification at E17.5 and birth, especially in the facial bones and the skull vault but normal ossification at three months. Our immunohistochemical analysis showed that the palatine bone osteoblast differentiation is delayed in Cx43I130T / + mice compared to their wildtype littermates, which contribute to the possibility of phenotypic variation observed in the facial bones.