Metabolic insights from a GHSR-A203E mutant mouse model.

Ghrelin binding to its receptor, growth hormone secretagogue receptor (GHSR) stimulates GH release, induce eating, and increase blood glucose. This process can also be influenced by the constitutive activity of GHSR (ghrelin-independent), as suggested by the findings of short stature in people with naturally occurring mutations GHSR-A204E and reduces food intake and blood glucose in rats given GHSR inverse agonists both harmful GHSR constitutive activity.

Here, we aim to further define the physiological relevance of constitutive GHSR activity.We GHSR generated mice with the mutation that replaces alanine at position 203 with glutamate (GHSR-A203E), in accordance with the A204E mutation-human GHSR above-referenced, and using them to perform ex vivo neuronal electrophysiology and in vivo assessment of metabolism. Also, we measure the signal in COS-7 and HEK293T cells transfected with wild-type GHSR (GHSR-WT) or construction GHSR-A203E.

RESULTS
In COS-7 cells, GHSR-A203E IP3 accumulation resulting lower base than GHSR-WT; ghrelin induced IP3 accumulation was observed for both construction. In HEK293T cells co-transfected with the voltage-gated CaVVVOur the data indicate that the A203E mutation ablates GHSR constitutive activity and constitutive activity GHSR original contribution to the conductance depolarizing GHSR-express NPY curve.

Although the A203E mutation does not block the ghrelin-generates a signal that is assessed using in vitro and ex vivo models, rat-A203E GHSR acute food shortages typically respond to ghrelin intake given in vivo. Also, GHSR-A203E mutation blunts GH release, and, in aged mice, leading to a decrease in body length and femur length, which is consistent with short stature human carrier GHSR-A204E mutation.

Effects of Alcohol and cocaine in Mutant Rat Model predisposition Post-Traumatic Stress Disorder

Comorbidity between substance abuse and post-traumatic stress disorder (PTSD), a stress-related dysregulation of fear responses, very high. While some drugs known to increase fear and anxiety, there are few data regarding the interaction between voluntary consumption of drugs and the fear memory.

Either spontaneous chronic consumption of alcohol or cocaine under 3 weeks of free choice progressive paradigm alcohol (3/6/10%) or cocaine (0.2 / 0.4 / 0.6 mg / ml), assessed in VGV transgenic mice, have full 5-HT2C receptor editing and displaying PTSD-like behaviors. The consequences of the consumption of these drugs on the potential contextual and cued fear conditioning response of VGV mice was assessed. Drug effects on hippocampal neurotrophic factor derived from the brain (BDNF) mRNA expression was measured as previously was found to decrease in VGV mice.

Chronic alcohol consumption was similar in WT and VGV mice. Under conditions of alcohol, the acquisition of fear is no different at the end of the learning session and cue-facilitated fear extinction. Regarding cocaine, in contrast to WT mice, rats VGV not improve their drug consumption along with increased dosage, effects that may be associated with stimulation of discrimination was increased through an increase in 5-HT2C receptor.

miRNA First-Strand cDNA Synthesis SuperMix
abx098020-20rxns20ulSystems	Abbexa	20 rxns × 20 ul Systems	EUR 878.4

Fly First-Strand cDNA Synthesis SuperMix
20-abx09885820ulSystems	Abbexa	EUR 861.60 EUR 693.60	100 rxns × 20 ul Systems 50 rxns × 20 ul Systems

Optimax First Strand cDNA Synthesis Kit
K4201100	Biochain	100 rnx	EUR 502.8

Human Adult Bladder (Normal) Whole tissue lysate
HAL-1310	Alpha Diagnostics	1 mg	EUR 628.8

Paraffin Tissue Section - Human Adult Normal: Bladder
T2234010	Biochain	5 slides	EUR 253.2
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Frozen Tissue Section - Human Adult Normal: Bladder
T1234010	Biochain	5 slides	EUR 418.8
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

cDNA from Monkey (Rhesus) Normal Tissue: Bladder
C1534010	Biochain	40 reactions	EUR 648
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Monkey (Cynomolgus) Normal Tissue: Bladder
C1534010-Cy	Biochain	40 reactions	EUR 648
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Adipose
C1234003-10	Biochain	10 reactions	EUR 277.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Adrenal
C1234004	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Brain
C1234035	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Breast
C1234086	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Colon
C1234090	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Esophagus
C1234106	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Heart
C1234122	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Kidney
C1234142	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Liver
C1234149	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Lung
C1234152	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Trachea
C1234160-10	Biochain	10 reactions	EUR 277.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Ovary
C1234183	Biochain	40 reactions	EUR 1126.8
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Pancreas
C1234188	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Placenta
C1234200	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Prostate
C1234201	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Rectum
C1234206	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Skin
C1234218	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Spleen
C1234246	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Stomach
C1234248	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Testis
C1234260	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Theca
C1234261-10	Biochain	10 reactions	EUR 277.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Throat
C1234263-10	Biochain	10 reactions	EUR 277.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Thymus
C1234264	Biochain	40 reactions	EUR 1126.8
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Thyroid
C1234265	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Tongue
C1234267-10	Biochain	10 reactions	EUR 277.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Tonsil
C1234268-10	Biochain	10 reactions	EUR 277.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Uterus
C1234274	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total Protein from Human Adult Normal Tissue: Bladder
P1234010	Biochain	1 mg	EUR 256.8
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Membrane Protein from Human Adult Normal Tissue: Bladder
P3234010	Biochain	0.1 mg	EUR 342
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Total RNA from Human Adult Normal Tissue: Bladder
R1234010-50	Biochain	50 ug	EUR 213.6
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

First-Strand cDNA Synthesis SuperMix for PCR
abx098018-50rxns20ulSystems	Abbexa	50 rxns × 20 ul Systems	EUR 693.6

cDNA from Human Adult Normal Tissue: Bone Marrow
C1234024-10	Biochain	10 reactions	EUR 277.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Brain: Amygdala
C1234036-10	Biochain	10 reactions	EUR 277.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Brain: Cerebellum
C1234039	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Brain: Hippocampus
C1234052-10	Biochain	10 reactions	EUR 324
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Brain: Pituitary
C1234068-10	Biochain	10 reactions	EUR 324
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Brain: Pons
C1234071-10	Biochain	10 reactions	EUR 277.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Colon Ascending
C1234091	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Colon Descending
C1234092	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Colon Sigmoid
C1234095	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Colon Transverse
C1234096	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Whole Eye
C1234108-10	Biochain	10 reactions	EUR 535.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Eye: Retina
C1234110-10	Biochain	10 reactions	EUR 535.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Fallopian Tube
C1234115-10	Biochain	10 reactions	EUR 277.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Lymph Node
C1234161-10	Biochain	10 reactions	EUR 277.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Skeletal Muscle
C1234171	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Salivary Gland
C1234212-10	Biochain	10 reactions	EUR 277.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Small Intestine
C1234226	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Spinal Cord
C1234234	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Stomach: Cardia
C1234250-10	Biochain	10 reactions	EUR 277.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Stomach: Corpus
C1234251-10	Biochain	10 reactions	EUR 277.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Stomach: Fundus
C1234252-10	Biochain	10 reactions	EUR 277.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Stomach: Pylorus
C1234253-10	Biochain	10 reactions	EUR 277.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Uterus: Cervix
C1234275	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Uterus: Corpus
C1234276-10	Biochain	10 reactions	EUR 277.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Uterus: Fundus
C1234278-10	Biochain	10 reactions	EUR 277.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

First-Strand cDNA Synthesis SuperMix (cDNA up to 12 kb)
20-abx09801620ulSystems	Abbexa	EUR 744.00 EUR 627.60	100 rxns × 20 ul Systems 50 rxns × 20 ul Systems

First-Strand cDNA Synthesis SuperMix (cDNA up to 15 kb)
20-abx09802120ulSystems	Abbexa	EUR 1045.20 EUR 794.40	100 rxns × 20 ul Systems 50 rxns × 20 ul Systems

igScript First Strand cDNA Synthesis Kit - 25 Reactions
4312	Intact Genomics	1/EA	EUR 178.8

igScript First Strand cDNA Synthesis Kit - 100 Reactions
4314	Intact Genomics	1/EA	EUR 453.6

Accuris qMAX First Strand cDNA Synthesis Flex Kit
PR2110-200	Benchmark Scientific	1 PC	EUR 405.3

Accuris qMAX First Strand cDNA Synthesis Flex Kit
PR2110-50	Benchmark Scientific	1 PC	EUR 159.35

Accuris qMAX First Strand cDNA Synthesis Flex Kit
PR2110-S	Benchmark Scientific	1 PC	EUR 87.58

Chicken (Normal/Adult) Universal (pool of tissue cDNA)
CHUC-565	Alpha Diagnostics	10 rxn	EUR 498

cDNA from Human Adult Normal Tissue: Blood Vessel: Artery
C1234013-10	Biochain	10 reactions	EUR 277.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Blood Vessel: Vein
C1234020-10	Biochain	10 reactions	EUR 277.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Brain: Cerebellum (left)
C1234040-10	Biochain	10 reactions	EUR 277.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Brain: Cerebellum (right)
C1234041-10	Biochain	10 reactions	EUR 277.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Brain: Cerebral Cortex
C1234042-10	Biochain	10 reactions	EUR 277.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Brain: Corpus Callosum
C1234045-10	Biochain	10 reactions	EUR 277.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Brain: Olfactory (region)
C1234063-10	Biochain	10 reactions	EUR 277.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Brain: Vermis Cerebelli
C1234082-10	Biochain	10 reactions	EUR 277.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Small Intestine: Duodenum
C1234101-10	Biochain	10 reactions	EUR 277.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Heart: Aorta Valve
C1234123-10	Biochain	10 reactions	EUR 277.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Heart: Atrium (left)
C1234126	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Heart: Atrium (right)
C1234127	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Heart: Ventricle (left)
C1234138	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Heart: Ventricle (right)
C1234139	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Peripheral Blood Leukocyte
C1234148-10	Biochain	10 reactions	EUR 277.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Liver: Left Lobe
C1234150	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Liver: Right Lobe
C1234151	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Small Intestine: Ileum
C1234227	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Small Intestine: Jejunum
C1234230	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Bladder Tissue Slide (Normal)
12-601-10um	ProSci	10 um	EUR 241.8

Bladder Tissue Slide (Normal)
12-601-4um	ProSci	4 um	EUR 216.6

Bladder Tissue Lysate (Normal)
1721-01	ProSci	0.1 mg	EUR 260.7
Description: Bladder tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 5% β-mercaptoethanol.

Human Adult cDNA Tissue: Lung
HA-152	Alpha Diagnostics	10 rxn	EUR 498

Human Adult cDNA Tissue: Skin
HA-218	Alpha Diagnostics	10 rxn	EUR 498

Human Adult cDNA Tissue: Testis
HA-260	Alpha Diagnostics	10 rxn	EUR 498

cDNA from Human Tumor Tissue: Bladder
C1235010-10	Biochain	10 reactions	EUR 338.4
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Lung: Left Lower Lobe
C1234155	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Lung: Left Upper Lobe
C1234156	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Lung: Right Lower Lobe
C1234157	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Lung: Right Middle Lobe
C1234158	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Adult Normal Tissue: Lung: Right Upper Lobe
C1234159	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Human Adult Normal Tissue 5 Donor Pool: Bladder
R1234010-P	Biochain	50 ug	EUR 393.6
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

All-in-One First-Strand cDNA Synthesis SuperMix for PCR
abx098023-50rxns20ulSystems	Abbexa	50 rxns × 20 ul Systems	EUR 878.4

Human Bladder Tissue Preparation Buffer 2: Normal Bladder Fibroblasts
9-80008	CHI Scientific	1 x 100 ml	Ask for price

Human Bladder Tissue Preparation Buffer 1: Normal Bladder Epithelial Cells
9-80007	CHI Scientific	1 x 100 ml	Ask for price

Mouse Bladder Tissue Preparation Buffer 2: Normal Bladder Fibroblasts
9-80121	CHI Scientific	1 x 100 ml	Ask for price

Rat Bladder Tissue Preparation Buffer 2: Normal Bladder Fibroblasts
9-80214	CHI Scientific	1 x 100 ml	Ask for price

cDNA from Mouse Normal Tissue: Adipose
C1334003	Biochain	40 reactions	EUR 648
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Mouse Normal Tissue: Brain
C1334035	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Mouse Normal Tissue: Colon
C1334090	Biochain	40 reactions	EUR 648
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Mouse Normal Tissue: Heart
C1334122	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Mouse Normal Tissue: Kidney
C1334142	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Mouse Normal Tissue: Liver
C1334149	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Mouse Normal Tissue: Lung
C1334152	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Mouse Normal Tissue: Placenta
C1334200	Biochain	40 reactions	EUR 648
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Mouse Normal Tissue: Rectum
C1334206	Biochain	40 reactions	EUR 648
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Mouse Normal Tissue: Spleen
C1334246	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Mouse Normal Tissue: Stomach
C1334248	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Mouse Normal Tissue: Testis
C1334260	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Rat Normal Tissue: Adipose
C1434003	Biochain	40 reactions	EUR 648
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Rat Normal Tissue: Brain
C1434035	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Rat Normal Tissue: Colon
C1434090	Biochain	40 reactions	EUR 648
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Rat Normal Tissue: Heart
C1434122	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Rat Normal Tissue: Kidney
C1434142	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Rat Normal Tissue: Liver
C1434149	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Rat Normal Tissue: Lung
C1434152	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Rat Normal Tissue: Placenta
C1434200	Biochain	40 reactions	EUR 648
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Rat Normal Tissue: Rectum
C1434206	Biochain	40 reactions	EUR 648
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Rat Normal Tissue: Spleen
C1434246	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Rat Normal Tissue: Stomach
C1434248	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Rat Normal Tissue: Testis
C1434260	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Dog Normal Tissue: Brain
C1734035	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Dog Normal Tissue: Cecum
C1734089	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Dog Normal Tissue: Esophagus
C1734106	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Dog Normal Tissue: Heart
C1734122	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Dog Normal Tissue: Kidney
C1734142	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Dog Normal Tissue: Liver
C1734149	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Dog Normal Tissue: Lung
C1734152	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Dog Normal Tissue: Trachea
C1734160	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Dog Normal Tissue: Pancreas
C1734188	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Dog Normal Tissue: Rectum
C1734206	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Dog Normal Tissue: Stomach
C1734248	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Dog Normal Tissue: Testis
C1734260	Biochain	40 reactions	EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Monkey (Cynomolgus) cDNA Normal Tissue: Liver
MC34-149	Alpha Diagnostics	10 rxn	EUR 498

Monkey (Cynomolgus) cDNA Normal Tissue: Pancreas
MC34-188	Alpha Diagnostics	10 rxn	EUR 498

Monkey (Cynomolgus) cDNA Normal Tissue: Spleen
MC34-246	Alpha Diagnostics	10 rxn	EUR 498

Human Bladder Tissue Preparation Buffer 3: Normal Bladder Smooth Muscle Cells
9-80009	CHI Scientific	1 x 100 ml	Ask for price

Human Bladder PrimaCell2: Normal Bladder Fibroblasts
2-96008	CHI Scientific	1 Kit	Ask for price

Mouse Bladder Tissue Preparation Buffer 1: Normal Bladder Epithelial Cells
9-80120	CHI Scientific	1 x 100 ml	Ask for price

Rat Bladder Tissue Preparation Buffer 1: Normal Bladder Epithelial Cells
9-80213	CHI Scientific	1 x 100 ml	Ask for price

Rtg T-Primed First-Strand Kit
27926301	Scientific Laboratory Supplies	EACH	EUR 750.12

Rtg You-Prime First-Strand Beads
27926401	Scientific Laboratory Supplies	EACH	EUR 489.06

cDNA from Plant Normal Tissue: cDNA from Plant: Arabidopsis
C1634310	Biochain	40 reactions	EUR 745.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Plant Normal Tissue: cDNA from Plant: Corn
C1634330	Biochain	40 reactions	EUR 745.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Plant Normal Tissue: cDNA from Plant: Orange
C1634340	Biochain	40 reactions	EUR 745.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Plant Normal Tissue: cDNA from Plant: Potato
C1634350	Biochain	40 reactions	EUR 745.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Plant Normal Tissue: cDNA from Plant: Rice
C1634360	Biochain	40 reactions	EUR 745.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Plant Normal Tissue: cDNA from Plant: Wheat
C1634390	Biochain	40 reactions	EUR 745.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Frozen Tissue Array - Human Adult Normal Tissue, Multi-tissue I
T6234700-1	Biochain	1 slide	EUR 337.2
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Frozen Tissue Array - Human Adult Normal Tissue, Multi-tissue I
T6234700-5	Biochain	5 slides	EUR 1112.4
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Cocaine-intake VGV mice do not display contextual generalization fear VGV usually observed in control rats. In addition, BDNF expression was upregulated after alcohol intake or chronic cocaine either. Overall, these results indicate that both chronic alcohol and cocaine consumption may exert some voluntary oral therapeutic effect in models like the mutants PTSD predisposition.