Metabolic insights from a GHSR-A203E mutant mouse model.

Ghrelin binding to its receptor, growth hormone secretagogue receptor (GHSR) stimulates GH release, induce eating, and increase blood glucose. This process can also be influenced by the constitutive activity of GHSR (ghrelin-independent), as suggested by the findings of short stature in people with naturally occurring mutations GHSR-A204E and reduces food intake and blood glucose in rats given GHSR inverse agonists both harmful GHSR constitutive activity.

Here, we aim to further define the physiological relevance of constitutive GHSR activity.We GHSR generated mice with the mutation that replaces alanine at position 203 with glutamate (GHSR-A203E), in accordance with the A204E mutation-human GHSR above-referenced, and using them to perform ex vivo neuronal electrophysiology and in vivo assessment of metabolism. Also, we measure the signal in COS-7 and HEK293T cells transfected with wild-type GHSR (GHSR-WT) or construction GHSR-A203E.

RESULTS
In COS-7 cells, GHSR-A203E IP3 accumulation resulting lower base than GHSR-WT; ghrelin induced IP3 accumulation was observed for both construction. In HEK293T cells co-transfected with the voltage-gated CaVVVOur the data indicate that the A203E mutation ablates GHSR constitutive activity and constitutive activity GHSR original contribution to the conductance depolarizing GHSR-express NPY curve.

Although the A203E mutation does not block the ghrelin-generates a signal that is assessed using in vitro and ex vivo models, rat-A203E GHSR acute food shortages typically respond to ghrelin intake given in vivo. Also, GHSR-A203E mutation blunts GH release, and, in aged mice, leading to a decrease in body length and femur length, which is consistent with short stature human carrier GHSR-A204E mutation.

Effects of Alcohol and cocaine in Mutant Rat Model predisposition Post-Traumatic Stress Disorder

Comorbidity between substance abuse and post-traumatic stress disorder (PTSD), a stress-related dysregulation of fear responses, very high. While some drugs known to increase fear and anxiety, there are few data regarding the interaction between voluntary consumption of drugs and the fear memory.

Either spontaneous chronic consumption of alcohol or cocaine under 3 weeks of free choice progressive paradigm alcohol (3/6/10%) or cocaine (0.2 / 0.4 / 0.6 mg / ml), assessed in VGV transgenic mice, have full 5-HT2C receptor editing and displaying PTSD-like behaviors. The consequences of the consumption of these drugs on the potential contextual and cued fear conditioning response of VGV mice was assessed. Drug effects on hippocampal neurotrophic factor derived from the brain (BDNF) mRNA expression was measured as previously was found to decrease in VGV mice.

Chronic alcohol consumption was similar in WT and VGV mice. Under conditions of alcohol, the acquisition of fear is no different at the end of the learning session and cue-facilitated fear extinction. Regarding cocaine, in contrast to WT mice, rats VGV not improve their drug consumption along with increased dosage, effects that may be associated with stimulation of discrimination was increased through an increase in 5-HT2C receptor.

Tissue cDNA, First Strand, Mouse Adult Normal, Bladder, BioGenomics
MBS652254-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Mouse Adult Normal, Bladder, BioGenomics
MBS652254-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Canine Adult Normal, Bladder, BioGenomics
MBS652449-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Canine Adult Normal, Bladder, BioGenomics
MBS652449-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Monkey (Rhesus) Adult Normal, Bladder, BioGenomics
MBS651900-40Tests	MyBiosource	40Tests	EUR 850

Tissue cDNA, First Strand, Monkey (Rhesus) Adult Normal, Bladder, BioGenomics
MBS651900-5x40Tests	MyBiosource	5x40Tests	EUR 3600

Tissue cDNA, First Strand, Monkey (Cynomolgus) Adult Normal, Bladder, BioGenomics
MBS652419-40Tests	MyBiosource	40Tests	EUR 850

Tissue cDNA, First Strand, Monkey (Cynomolgus) Adult Normal, Bladder, BioGenomics
MBS652419-5x40Tests	MyBiosource	5x40Tests	EUR 3600

Tissue cDNA, First Strand, Human Adult Normal, Skin, BioGenomics
MBS651946-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Skin, BioGenomics
MBS651946-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Human Adult Normal, Lung, BioGenomics
MBS652185-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Lung, BioGenomics
MBS652185-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Human Adult Normal, Liver, BioGenomics
MBS651906-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Liver, BioGenomics
MBS651906-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Human Adult Normal, Brain, BioGenomics
MBS652047-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Brain, BioGenomics
MBS652047-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Human Adult Normal, Theca, BioGenomics
MBS652079-10Tests	MyBiosource	10Tests	EUR 540

Tissue cDNA, First Strand, Human Adult Normal, Theca, BioGenomics
MBS652079-5x10Tests	MyBiosource	5x10Tests	EUR 2215

Tissue cDNA, First Strand, Human Adult Normal, Heart, BioGenomics
MBS652300-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Heart, BioGenomics
MBS652300-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Human Adult Normal, Colon, BioGenomics
MBS652410-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Colon, BioGenomics
MBS652410-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Human Adult Normal, Uterus, BioGenomics
MBS651999-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Uterus, BioGenomics
MBS651999-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Human Adult Normal, Testis, BioGenomics
MBS652030-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Testis, BioGenomics
MBS652030-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Human Adult Normal, Breast, BioGenomics
MBS652083-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Breast, BioGenomics
MBS652083-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Human Adult Normal, Spleen, BioGenomics
MBS652259-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Spleen, BioGenomics
MBS652259-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Human Adult Normal, Kidney, BioGenomics
MBS652261-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Kidney, BioGenomics
MBS652261-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Human Adult Normal, Tonsil, BioGenomics
MBS652456-10Tests	MyBiosource	10Tests	EUR 540

Tissue cDNA, First Strand, Human Adult Normal, Tonsil, BioGenomics
MBS652456-5x10Tests	MyBiosource	5x10Tests	EUR 2215

Tissue cDNA, First Strand, Human Adult Normal, Tongue, BioGenomics
MBS652491-10Tests	MyBiosource	10Tests	EUR 540

Tissue cDNA, First Strand, Human Adult Normal, Tongue, BioGenomics
MBS652491-5x10Tests	MyBiosource	5x10Tests	EUR 2215

Tissue cDNA, First Strand, Human Adult Normal, Throat, BioGenomics
MBS652534-10Tests	MyBiosource	10Tests	EUR 540

Tissue cDNA, First Strand, Human Adult Normal, Throat, BioGenomics
MBS652534-5x10Tests	MyBiosource	5x10Tests	EUR 2215

Tissue cDNA, First Strand, Human Adult Normal, Rectum, BioGenomics
MBS652577-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Rectum, BioGenomics
MBS652577-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Human Adult Normal, Stomach, BioGenomics
MBS651867-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Stomach, BioGenomics
MBS651867-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Human Adult Normal, Adrenal, BioGenomics
MBS651970-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Adrenal, BioGenomics
MBS651970-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Human Adult Normal, Adipose, BioGenomics
MBS652135-10Tests	MyBiosource	10Tests	EUR 540

Tissue cDNA, First Strand, Human Adult Normal, Adipose, BioGenomics
MBS652135-5x10Tests	MyBiosource	5x10Tests	EUR 2215

Tissue cDNA, First Strand, Human Adult Normal, Thyroid, BioGenomics
MBS652574-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Thyroid, BioGenomics
MBS652574-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Human Adult Normal, Duodenum, BioGenomics
MBS651927-10Tests	MyBiosource	10Tests	EUR 540

Tissue cDNA, First Strand, Human Adult Normal, Duodenum, BioGenomics
MBS651927-5x10Tests	MyBiosource	5x10Tests	EUR 2215

Tissue cDNA, First Strand, Human Adult Normal, Pancreas, BioGenomics
MBS652189-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Pancreas, BioGenomics
MBS652189-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Human Adult Normal, Placenta, BioGenomics
MBS652328-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Placenta, BioGenomics
MBS652328-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Human Adult Normal, Prostate, BioGenomics
MBS652399-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Prostate, BioGenomics
MBS652399-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Human Adult Normal, Esophagus, BioGenomics
MBS652478-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Esophagus, BioGenomics
MBS652478-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Human Adult Normal, Eye, Whole, BioGenomics
MBS652434-10Tests	MyBiosource	10Tests	EUR 750

Tissue cDNA, First Strand, Human Adult Normal, Eye, Whole, BioGenomics
MBS652434-5x10Tests	MyBiosource	5x10Tests	EUR 3145

Tissue cDNA, First Strand, Human Adult Normal, Lymph node, BioGenomics
MBS652078-10Tests	MyBiosource	10Tests	EUR 540

Tissue cDNA, First Strand, Human Adult Normal, Lymph node, BioGenomics
MBS652078-5x10Tests	MyBiosource	5x10Tests	EUR 2215

Tissue cDNA, First Strand, Human Adult Normal, Brain, Pons, BioGenomics
MBS652299-10Tests	MyBiosource	10Tests	EUR 540

Tissue cDNA, First Strand, Human Adult Normal, Brain, Pons, BioGenomics
MBS652299-5x10Tests	MyBiosource	5x10Tests	EUR 2215

Tissue cDNA, First Strand, Human Adult Normal, Bone Marrow, BioGenomics
MBS652385-10Tests	MyBiosource	10Tests	EUR 540

Tissue cDNA, First Strand, Human Adult Normal, Bone Marrow, BioGenomics
MBS652385-5x10Tests	MyBiosource	5x10Tests	EUR 2215

Tissue cDNA, First Strand, Human Adult Normal, Spinal cord, BioGenomics
MBS652436-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Spinal cord, BioGenomics
MBS652436-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Human Adult Normal, Lung, Trachea, BioGenomics
MBS652253-10Tests	MyBiosource	10Tests	EUR 540

Tissue cDNA, First Strand, Human Adult Normal, Lung, Trachea, BioGenomics
MBS652253-5x10Tests	MyBiosource	5x10Tests	EUR 2215

Tissue cDNA, First Strand, Human Adult Normal, Uterus, Cervix, BioGenomics
MBS651890-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Uterus, Cervix, BioGenomics
MBS651890-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Human Adult Normal, Stomach, Fundus, BioGenomics
MBS651912-10Tests	MyBiosource	10Tests	EUR 540

Tissue cDNA, First Strand, Human Adult Normal, Stomach, Fundus, BioGenomics
MBS651912-5x10Tests	MyBiosource	5x10Tests	EUR 2215

Tissue cDNA, First Strand, Human Adult Normal, Salivary gland, BioGenomics
MBS652022-10Tests	MyBiosource	10Tests	EUR 540

Tissue cDNA, First Strand, Human Adult Normal, Salivary gland, BioGenomics
MBS652022-5x10Tests	MyBiosource	5x10Tests	EUR 2215

Tissue cDNA, First Strand, Human Adult Normal, Stomach, Cardia, BioGenomics
MBS652430-10Tests	MyBiosource	10Tests	EUR 540

Tissue cDNA, First Strand, Human Adult Normal, Stomach, Cardia, BioGenomics
MBS652430-5x10Tests	MyBiosource	5x10Tests	EUR 2215

Tissue cDNA, First Strand, Human Adult Normal, Uterus, Corpus, BioGenomics
MBS652435-10Tests	MyBiosource	10Tests	EUR 540

Tissue cDNA, First Strand, Human Adult Normal, Uterus, Corpus, BioGenomics
MBS652435-5x10Tests	MyBiosource	5x10Tests	EUR 2215

Tissue cDNA, First Strand, Human Adult Normal, Uterus, Fundus, BioGenomics
MBS652490-10Tests	MyBiosource	10Tests	EUR 540

Tissue cDNA, First Strand, Human Adult Normal, Uterus, Fundus, BioGenomics
MBS652490-5x10Tests	MyBiosource	5x10Tests	EUR 2215

Tissue cDNA, First Strand, Human Adult Normal, Colon sigmoid, BioGenomics
MBS652527-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Colon sigmoid, BioGenomics
MBS652527-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Human Adult Normal, Stomach, Corpus, BioGenomics
MBS652550-10Tests	MyBiosource	10Tests	EUR 540

Tissue cDNA, First Strand, Human Adult Normal, Stomach, Corpus, BioGenomics
MBS652550-5x10Tests	MyBiosource	5x10Tests	EUR 2215

Tissue cDNA, First Strand, Human Adult Normal, Fallopian Tube, BioGenomics
MBS652556-10Tests	MyBiosource	10Tests	EUR 540

Tissue cDNA, First Strand, Human Adult Normal, Fallopian Tube, BioGenomics
MBS652556-5x10Tests	MyBiosource	5x10Tests	EUR 2215

Tissue cDNA, First Strand, Human Adult Normal, Brain, Thalamus, BioGenomics
MBS652560-10Tests	MyBiosource	10Tests	EUR 495

Tissue cDNA, First Strand, Human Adult Normal, Brain, Thalamus, BioGenomics
MBS652560-40Tests	MyBiosource	40Tests	EUR 775

Tissue cDNA, First Strand, Human Adult Normal, Brain, Thalamus, BioGenomics
MBS652560-5x40Tests	MyBiosource	5x40Tests	EUR 3270

Tissue cDNA, First Strand, Human Adult Normal, Brain, Amygdala, BioGenomics
MBS652587-10Tests	MyBiosource	10Tests	EUR 540

Tissue cDNA, First Strand, Human Adult Normal, Brain, Amygdala, BioGenomics
MBS652587-5x10Tests	MyBiosource	5x10Tests	EUR 2215

Tissue cDNA, First Strand, Human Adult Normal, Brain, Pituitary, BioGenomics
MBS651901-10Tests	MyBiosource	10Tests	EUR 550

Tissue cDNA, First Strand, Human Adult Normal, Brain, Pituitary, BioGenomics
MBS651901-5x10Tests	MyBiosource	5x10Tests	EUR 2255

Tissue cDNA, First Strand, Human Adult Normal, Colon descending, BioGenomics
MBS652112-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Colon descending, BioGenomics
MBS652112-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Human Adult Normal, Colon ascending, BioGenomics
MBS652290-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Colon ascending, BioGenomics
MBS652290-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Human Adult Normal, Stomach, Pylorus, BioGenomics
MBS652462-10Tests	MyBiosource	10Tests	EUR 540

Tissue cDNA, First Strand, Human Adult Normal, Stomach, Pylorus, BioGenomics
MBS652462-5x10Tests	MyBiosource	5x10Tests	EUR 2215

Tissue cDNA, First Strand, Human Adult Normal, Colon transverse, BioGenomics
MBS652512-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Colon transverse, BioGenomics
MBS652512-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Human Adult Normal, Skeletal Muscle, BioGenomics
MBS652565-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Skeletal Muscle, BioGenomics
MBS652565-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Human Adult Normal, Small intestine, BioGenomics
MBS652588-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Small intestine, BioGenomics
MBS652588-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Rat Adult Normal, Lung, BioGenomics
MBS652470-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Rat Adult Normal, Lung, BioGenomics
MBS652470-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Rat Adult Normal, Brain, BioGenomics
MBS651977-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Rat Adult Normal, Brain, BioGenomics
MBS651977-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Rat Adult Normal, Heart, BioGenomics
MBS651984-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Rat Adult Normal, Heart, BioGenomics
MBS651984-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Rat Adult Normal, Liver, BioGenomics
MBS652095-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Rat Adult Normal, Liver, BioGenomics
MBS652095-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Rat Adult Normal, Colon, BioGenomics
MBS652432-40Tests	MyBiosource	40Tests	EUR 850

Tissue cDNA, First Strand, Rat Adult Normal, Colon, BioGenomics
MBS652432-5x40Tests	MyBiosource	5x40Tests	EUR 3600

Tissue cDNA, First Strand, Human Adult Normal, Brain, Hippocampus, BioGenomics
MBS651929-10Reactions	MyBiosource	10Reactions	EUR 550

Tissue cDNA, First Strand, Human Adult Normal, Brain, Hippocampus, BioGenomics
MBS651929-5x10Reactions	MyBiosource	5x10Reactions	EUR 2255

Tissue cDNA, First Strand, Mouse Adult Normal, Lung, BioGenomics
MBS652000-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Mouse Adult Normal, Lung, BioGenomics
MBS652000-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Rat Adult Normal, Rectum, BioGenomics
MBS652009-40Tests	MyBiosource	40Tests	EUR 850

Tissue cDNA, First Strand, Rat Adult Normal, Rectum, BioGenomics
MBS652009-5x40Tests	MyBiosource	5x40Tests	EUR 3600

Tissue cDNA, First Strand, Rat Adult Normal, Kidney, BioGenomics
MBS652090-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Rat Adult Normal, Kidney, BioGenomics
MBS652090-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Rat Adult Normal, Spleen, BioGenomics
MBS652466-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Rat Adult Normal, Spleen, BioGenomics
MBS652466-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Rat Adult Normal, Testis, BioGenomics
MBS652483-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Rat Adult Normal, Testis, BioGenomics
MBS652483-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Human Adult Normal, Liver, Left Lobe, BioGenomics
MBS652382-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Liver, Left Lobe, BioGenomics
MBS652382-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Mouse Adult Normal, Liver, BioGenomics
MBS651975-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Mouse Adult Normal, Liver, BioGenomics
MBS651975-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Mouse Adult Normal, Brain, BioGenomics
MBS651994-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Mouse Adult Normal, Brain, BioGenomics
MBS651994-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Canine Adult Normal, Lung, BioGenomics
MBS652012-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Canine Adult Normal, Lung, BioGenomics
MBS652012-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Rat Adult Normal, Adipose, BioGenomics
MBS652230-40Tests	MyBiosource	40Tests	EUR 850

Tissue cDNA, First Strand, Rat Adult Normal, Adipose, BioGenomics
MBS652230-5x40Tests	MyBiosource	5x40Tests	EUR 3600

Tissue cDNA, First Strand, Mouse Adult Normal, Colon, BioGenomics
MBS652314-40Tests	MyBiosource	40Tests	EUR 850

Tissue cDNA, First Strand, Mouse Adult Normal, Colon, BioGenomics
MBS652314-5x40Tests	MyBiosource	5x40Tests	EUR 3600

Tissue cDNA, First Strand, Rat Adult Normal, Stomach, BioGenomics
MBS652326-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Rat Adult Normal, Stomach, BioGenomics
MBS652326-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Mouse Adult Normal, Heart, BioGenomics
MBS652497-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Mouse Adult Normal, Heart, BioGenomics
MBS652497-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Human Adult Normal, Heart, Aorta Valve, BioGenomics
MBS651939-10Tests	MyBiosource	10Tests	EUR 540

Tissue cDNA, First Strand, Human Adult Normal, Heart, Aorta Valve, BioGenomics
MBS651939-5x10Tests	MyBiosource	5x10Tests	EUR 2215

Tissue cDNA, First Strand, Human Adult Normal, Blood vessel, Vein, BioGenomics
MBS652064-10Tests	MyBiosource	10Tests	EUR 540

Tissue cDNA, First Strand, Human Adult Normal, Blood vessel, Vein, BioGenomics
MBS652064-5x10Tests	MyBiosource	5x10Tests	EUR 2215

Tissue cDNA, First Strand, Human Adult Normal, Heart, Atrium (left), BioGenomics
MBS652342-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Heart, Atrium (left), BioGenomics
MBS652342-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Human Adult Normal, Liver, Right Lobe, BioGenomics
MBS652391-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Human Adult Normal, Liver, Right Lobe, BioGenomics
MBS652391-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Canine Adult Normal, Brain, BioGenomics
MBS651872-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Canine Adult Normal, Brain, BioGenomics
MBS651872-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Mouse Adult Normal, Testis, BioGenomics
MBS652051-40Tests	MyBiosource	40Tests	EUR 680

Tissue cDNA, First Strand, Mouse Adult Normal, Testis, BioGenomics
MBS652051-5x40Tests	MyBiosource	5x40Tests	EUR 2835

Tissue cDNA, First Strand, Rat Adult Normal, Placenta, BioGenomics
MBS652126-40Tests	MyBiosource	40Tests	EUR 850

Tissue cDNA, First Strand, Rat Adult Normal, Placenta, BioGenomics
MBS652126-5x40Tests	MyBiosource	5x40Tests	EUR 3600

Tissue cDNA, First Strand, Rat Adult Normal, Pancreas, BioGenomics
MBS652162-40Tests	MyBiosource	40Tests	EUR 905

Tissue cDNA, First Strand, Rat Adult Normal, Pancreas, BioGenomics
MBS652162-5x40Tests	MyBiosource	5x40Tests	EUR 3845

Tissue cDNA, First Strand, Mouse Adult Normal, Rectum, BioGenomics
MBS652184-40Tests	MyBiosource	40Tests	EUR 850

Cocaine-intake VGV mice do not display contextual generalization fear VGV usually observed in control rats. In addition, BDNF expression was upregulated after alcohol intake or chronic cocaine either. Overall, these results indicate that both chronic alcohol and cocaine consumption may exert some voluntary oral therapeutic effect in models like the mutants PTSD predisposition.